台南厝邊好醫師: 醫學研究

目前主要服務於診所，另一方面也取得台大醫學院生理學研究所的博士學位，積極進行醫學研究。

論文發表

1. Chen CY, Lin LY, Lin JL. Direct mechanoelectrical coupling during manual chest compression for asystole. Heart Rhythm. 2015 Jan;12(1):252-3.
2. Jimmy JJ, Chen CY, Yeh HM, Chiu WY, Yu CC, Liu YB, Tsai CT, Lo LW, Yeh SF, Lai LP. Clinical characteristics of patients with congenital long QT syndrome and bigenic mutations. Chin Med J (Engl). 2014;127(8):1482-6.
3. Jyh-Ming Jimmy Juang, Ching-Yu Chen, Yen-Bin Liu, Lian-Yu Lin, Wen-Jone Chen, Ling-Ping Lai. Prevalence of Atrial Fibrillation in Patients with Brugada Syndrome in Taiwan. Acta Cardiol Sin 2013;29:311316.
4. Juang JM, Chen CY, Chen YH, Wu IC, Hsu CC, Chen LN, Tang FC, Wang CC, Juan CC, Chiu HC, Lo HM, Chang IS, Hwang JJ, Lai LP, Chiang FT, Lin JL, Hsiung CA. Prevalence and prognosis of Brugada electrocardiogram patterns in an elderly Han Chinese population: a nation-wide community-based study (HALST cohort). Europace. 2015 Oct;17 Suppl 2:ii54-ii62. doi: 10.1093/europace/euv141.
5. Dun-Hui Yang, Ching-Yu Julius Chen. Concomitant pulsus and pseudoelectrical alternans in severe systolic dysfunction. HeartRhythm Case Report 2016;2:277-279.
6. Chen CJ (Ching-Yu Julius), Juang JJ, Chen YH, Wu IC, Hsu CC, Wu RC, Chen KC, Liaw WJ, Tsai TL, Lin LY, Hwang JJ, Ho LT, Yu CC, Lee JK, Wu CK, Yeh SS, Yang DH, Chang IS, Lai LP, Chiang FT, Lin JL, Hsiung CA. Comparisons of clinical impacts on individuals with Brugada electrocardiographic patterns defined by ISHNE criteria or EHRA/HRS/APHRS criteria: a nationwide community-based study. Ann Med. 2017 Jul 18:1-9. doi: 10.1080/07853890.2017.1353222.
7. Ching-Yu Julius Chen, Tzu-Ching Yang, Christopher Chang, Shao-Chun Lu and Po-Yuan Chang. Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study. BMC Cardiovascular Disorders (2018) 18:33 https://doi.org/10.1186/s12872-018-0774-8
8. Can Hasdemir, Jimmy Jyh‐Ming Juang, Sedat Kose, Umut Kocabas, Mehmet N. Orman, Serdar Payzin, Hatice Sahin, Candan Celen, Emin E. Ozcan, Ching‐Yu Julius Chen, Ramazan Gunduz, Oguzhan E. Turan, Oktay Senol Elena Burashnikov, Charles Antzelevitch. Coexistence of atrioventricular accessory pathways and drug‐induced type 1 Brugada pattern. Pacing Clin Electrophysiol. 2018 Jun 28. doi: 10.1111/pace.13414
9. Ching-Yu Julius Chen, Tzu-Pin Lu, Lian-Yu Lin, Yen-Bin Liu, Li-Ting Ho, Hui-Chun Huang, Ling-Ping Lai, Juey-Jen Hwang, Shih-Fan Sherri Yeh, Cho-Kai Wu, Jyh-Ming Jimmy Juang* and Charles Antzelevitch. Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients with Brugada Syndrome in the Genomic Era: a SADS-TW BrS Registry. Front. Genet. 9:680 doi: 10.3389/fgene.2018.00680. Published: 04 January 2019.
10. Ching-Yu Julius Chen, Jyh-Ming Jimmy Juang, Lian-Yu Lin, Yen-Bin Liu, Li-Ting Ho, Chih-Chieh Yu, Hui-Chun Huang, Ting-Tse Lin, Ming-Chun Liao, Jien-Jiun Chen, Juey-Jen Hwang, Wen-Jone Chen, Shih-Fan Sherri Yeh, Dun-Hui Yang, Fu-Tien Chiang, Jiunn-Lee Lin, Ling-Ping Lai, Minoru Horie (SADS-TW BrS Registry). Gender Difference in Clinical and Genetic Characteristics of Brugada Syndrome: SADS-TW BrS Registry. QJM: An International Journal of Medicine. Published: 08 Feburary 2019.

11.Sherri Shih-Fan Yeh, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Feng-Cheng Tang, Chi-Chung Wang, Chung-Chou Juan, Hou-Chang Chiu, Huey-Ming Lo, Dun-Hui Yang, Chao Agnes Hsiung. The 10-Year prognosis and prevalence of Brugada-type electrocardiograms in elderly women: a longitudinal nationwide community-based prospective study. The Journal of Cardiovascular Nursing. Nov/Dec 2020;35(6):E25-E32. doi: 10.1097/JCN.0000000000000722.

12.Jyh-Ming Jimmy Juang, Yen-Bin Liu, Ching-Yu Julius Chen, Qi-You Yu, Amrita Chattopadhyay, Lian-Yu Lin, Wen-Jone Chen, Chih-Chieh Yu, Hui-Chun Huang, Li-Ting Ho, Ling-Ping Lai, Juey-Jen Hwang, Ting-Tse Lin, Ming-Chun Liao, Jien-Jiun Chen, Shih-Fan Sherri Yeh, Jing-Yuan Chuang, Dun-Hui Yang, Jiunn-Lee Lin, Tzu-Pin Lu, Eric Y. Chuang, and Michael J. Ackerman. Validation and Disease Risk Assessment of Previously Reported Genome-Wide Genetic Variants Associated with Brugada Syndrome: SADS-TW BrS Registry. Cirucation: Genomic and Precision Medicine. 2020 Jun 3. doi: 10.1161/CIRCGEN.119.002797.
13. Sherri Shih-Fan Yeh, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Feng-Cheng Tang, Chi-Chung Wang, Chung-Chou Juan, Hou-Chang Chiu, Huey-Ming Lo, Dun-Hui Yang, Jyh-Ming Jimmy Juang, Chao Agnes Hsiung. Prognostic value and prevalence of complete right bundle branch block in an elderly population: a community-based 10-year prospective study. Aging. 2020 Oct 6;12(19):19073-19082. doi: 10.18632/aging.103702. Online ahead of print.
14. Jyh-Ming Jimmy Juang, Anna Binda, Shyh-Jye Lee, Juey-Jen Hwang, Wen-Jone Chen, Yen-Bin Liu, Lian-Yu Lin, Chih-Chieh Yu, Li-Ting Ho, Hui-Chun Huang, Ching-Yu Julius Chen, Tzu-Pin Lu, Liang-Chuan Lai, Shih-Fan Sherri Yeh, Ling-Ping Lai, Eric Y. Chuang, Ilaria Rivolta, Charles Antzelevitch. GSTM3 variant is a novel genetic modiﬁer in Brugada syndrome, a disease with risk of sudden cardiac death. EBioMedicine 57 (2020) 102843. https://doi.org/10.1016/j.ebiom.2020.102843
15. Sherri Shih-Fan Yeh, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Feng-Cheng Tang, Chi-Chung Wang, Chung-Chou Juan, Hou-Chang Chiu, Huey-Ming Lo, Dun-Hui Yang, Jyh-Ming Jimmy Juang, Chao Agnes Hsiung. The 10-Year Prognosis and Prevalence of Brugada-Type Electrocardiograms in Elderly Women A Longitudinal Nationwide Community-Based Prospective Study. Journal of Cardiovascular Nursing. June 23, 2020. doi: 10.1097/JCN.0000000000000722.
16. Tzu-Pin Lu; Ming-Wei Su; Jenn-Hwai Yang; Hou-Wei Chu; Chien-Hsiun Chen; Yi-Wen Hsiao; Chien-Yueh Lee; Li-Mei Chiang; Qi-You Yu; Chuh-Hsing K. Hsiao; Ching-Yu Julius Chen; Pei-Ei Wu; Chien-Hua Pai; Eric Y. Chuang; Chen-Yang Shen. Rare variants discovery by extensive whole-genome sequencing of the Han Chinese population in Taiwan: applications to cardiovascular medicine. Journal of Advanced Research. 2020 Dec 7;30:147-158. doi: 10.1016/j.jare.2020.12.003. eCollection 2021 May.

17. Jyh-Ming Jimmy Juang, Yu-Jyun Huang, I-Shou Chang, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Shih-Fan Sherri Yeh, Chao Agnes Hsiung. Role of electrocardiographic early repolarization pattern in long-term outcomes of a community-based middle-aged and geriatric ambulatory population: a prospective cohort study. Aging. 2020 Dec 19;12(24):26140-26187. doi: 10.18632/aging.202369. Epub 2020 Dec 19.

18. Ching-Yu Julius Chen, Mao-Yuan Marine Su, Ying-Chieh Liao, Fu-Lan Chang, Cho-Kai Wu, Lian-Yu Lin, Yih-Shurng Chen, Yen-Hung Lin, Juey-Jen Hwang, Sung-Liang Yu, Hsien-Li Kao, Wen-Jone Chen, Tzu-Pin Lu, Ching-Yu Shih, Shih-Fan Sherri Yeh, Dun-Hui Yang, Ling-Ping Lai, Jyh-Ming Jimmy Juang. Long-term outcomes and left ventricular diastolic function of sarcomere mutation-positive and mutation-negative patients with hypertrophic cardiomyopathy: a prospective cohort study. Eur Heart J Cardiovasc Imaging. 2020 Nov 22;jeaa317. doi: 10.1093/ehjci/jeaa317. Online ahead of print.

19. Jyh-Ming Jimmy Juang, Anna Binda, Shyh-Jye Lee, Juey-Jen Hwang, Wen-Jone Chen, Yen-Bin Liu, Lian-Yu Lin, Chih-Chieh Yu, Li-Ting Ho, Hui-Chun Huang, Ching-Yu Julius Chen, Tzu-Pin Lu, Liang-Chuan Lai, Shih-Fan Sherri Yeh, Ling-Ping Lai, Eric Y Chuang, Ilaria Rivolta, Charles Antzelevitch. GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death. EBioMedicine. 2020 Jul;57:102843. doi: 10.1016/j.ebiom.2020.102843. Epub 2020 Jul 7.

20. Tzu Pin Lu, Amrita Chattopadhyay, Jing-Yuan Chuang, Shih-Fan Sherri Yeh, I-Shou Chang, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Chao Agnes Hsiung, Jyh-Ming Jimmy Juang. Develop and Apply Electrocardiography-based Risk Score to Identify Community-Based Elderly Individuals at High-Risk of Mortality. Front. Cardiovasc. Med., 08 October 2021 | https://doi.org/10.3389/fcvm.2021.738061

翻譯

1. 心臟學：探究臨床案例《Cardiology: Clinical Cases Uncovered》
2. 心電圖快速解讀《RAPID INTERPRETATION OF EKG's》
3. 臨床心電圖學必讀《Making Sense of the ECG》

國際研討會

2018/10/20 亞太心律學會 (APHRS) @ 台北

在國際會議上發表布魯蓋達症候群 (Brugada syndrome) 在男女之間的表現差異。後來得到最佳海報獎 (Best Poster Award) 的殊榮。

2018/05/20 亞太心臟學大會 (APSC) @ 台北

我們團隊發現布魯蓋達症候群 (Brugada syndrome) 的病患如果帶有致心律不整性右心室心肌病變 (arrhythmogenic right ventricular cardiomyopathy, ARVC) 相關的基因突變，其右心室的收縮力反而較佳，代表相同的基因產生突變可能導致截然不同的表現形態。